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THE GENERATION DIAGNOSTIC SYSTEM
A Microalbumin test evaluates urine for the presence of a protein called albumin. Albumin is normally found in the blood and filtered by the kidneys. When the kidneys are working properly, albumin is not present in the urine. However, when the kidneys are damaged, small amounts of albumin leak into the urine. This condition is called Microalbumin.[1-4] Microalbumin is most frequently caused by kidney damage from diabetes. However, many other conditions can lead to kidney damage, such as high blood pressure, heart failure, cirrhosis, or systemic lupus erythmatosus(SLE). If kidney damage is not treated at an early stage, larger amounts of albumin and protein may leak into the urine.[5,6] This condition is called macroalbuminuria or proteinuria. When the kidneys spill protein, it can mean serious kidney damage is present. This can lead to chronic kidney disease. A microalbumin urine test can be done on a sample of urine collected randomly (usually after the first time you urinate in the morning), a sample collected over a 24-hour period, or a sample collected over a specific period of time, such as 4 hours or overnight.
- 1.Rowe DJF, Dawnay A, Watts GF. Microalbumin in diabetes mellitus: review and recommendations for the measurement of albumin in urine. Ann Clin Biochem 1990; 27: 297-312.
- 2.Doumas BT, Peters T. Serum and urine albumin: a progress report on their measurement and clinical significance. Clin Chim Acta 1997; 258:3-20.
- 3. Mogensen CE. Microalbumin, a marker for organ damage. 1993. London: Science Press.
- 4.Waugh J, Kilby M, Lambert P, Bell SC, Blackwell CN, Shennan A, et al. Validation of the DCA 2000 microalbumin:creatinine ratio urinanalyzer for its use in pregnancy and preeclampsia. Hypertens Pregnancy 2003; 22(1): 77-92.
- 5.Mogensen CE, Christnesen CK. Predicting diabetic nephropathy in insulin dependent diabetes. New Eng J Med 1984; 311:89-93.
- 6.Viberti GC, Hill RD, Jarrett RJ. Microalbumin as a predictor of clinical nephropathy in insulin dependent diabetes mellitus. Lancet 1982;I: 1430-2.
- 7.Viberti GC, Hill RD, Jarrett RJ. Microalbumin as a predictor of clinical nephropathy in insulin dependent diabetes mellitus. Lancet 1982;I: 1430-2.
|Detection Range||2~300 mg/L|